OMG Antikörper (AA 260-340)

Produktnummer ABIN7216318

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch OMG in ELISA, WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für OMG Antikörper (AA 260-340) (ABIN7216318)

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OMG Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-OMG Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: OMG Polyclonal Antibody

Spezifität: OMG Polyclonal Antibody detects endogenous levels of OMG protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human OMG at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu OMG

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Andere Bezeichnung: OMG

Hintergrund: Rabbit Anti-OMG Polyclonal Antibody,OMG, OMGP, Oligodendrocyte-myelin glycoprotein,Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.,Oligodendrocyte-myelin glycoprotein

Molekulargewicht: observerd band 48kDa

Gen-ID: 4974

UniProt: P23515

Pathways: Neurotrophin Signalübertragung, Regulation of Cell Size