NMDA epsilon 1/2 (pTyr1246), (pTyr1252) Antikörper

Produktnummer ABIN7221330

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NMDA epsilon 1/2 in ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NMDA epsilon 1/2 (pTyr1246), (pTyr1252) Antikörper (ABIN7221330)

Target: NMDA epsilon 1/2

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: pTyr1246, pTyr1252

Verwendungszweck: NMDAε1/2 (phospho Tyr1246/1252) Polyclonal Antibody

Spezifität: Phospho-NMDAε1/2 (Y1246/1252) Polyclonal Antibody detects endogenous levels of NMDAε1/2 protein only when phosphorylated at Y1246/1252.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human NMDAepsilon1/2 Phospho-Tyr1246/1252

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: NMDA epsilon 1/2

Andere Bezeichnung: NMDAepsilon1/2

Hintergrund: Rabbit Anti-NMDAε1/2 (phospho Tyr1246/1252) Polyclonal Antibody,GRIN2A, NMDAR2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2B, NMDAR2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, N,GRIN2A encodes a member of the glutamate-gated ion channel protein family. The glutamate ionotropic receptor NMDA type subunit 2A is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.,Glutamate [NMDA] receptor subunit epsilon-1

Gen-ID: 2903, 2904