NKX2-8 Antikörper (AA 10-90)

Produktnummer ABIN7220988

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NKX2-8 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NKX2-8 Antikörper (AA 10-90) (ABIN7220988)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NKX2-8 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Nkx-2.8 Polyclonal Antibody

Spezifität: Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Nkx-2.8 at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: Nkx-2.8

Hintergrund: Rabbit Anti-Nkx-2.8 Polyclonal Antibody,The NK2 homeobox 8 encoded by NKX2-8 is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.,Homeobox protein Nkx-2.8

Molekulargewicht: observerd band 26kDa

Gen-ID: 26257

UniProt: Q8IUT7