Nkx2-2 Antikörper

Produktnummer ABIN7230018

Der Kaninchen Polyklonal anti-Nkx2-2 Antikörper wird verwendet zum Nachweis von Nkx2-2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Nkx2-2 Antikörper (ABIN7230018)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Nkx2-2 Antikörper

Verwendungszweck: Rabbit Anti-NKX22 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NKX22 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NKX22 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: NKX22

Hintergrund: Homeobox protein Nkx-2.2, Homeobox protein NK-2 homolog BNKX2-2 (NK2 Homeobox 2) is a Protein Coding gene. Diseases associated with NKX2-2 include Maturity-Onset Diabetes Of The Young and Oligodendroglioma. Among its related pathways are Regulation of beta-cell development and Dopaminergic Neurogenesis. The protein encoded by NKX2-2 contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. NKX2-2 is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.

Molekulargewicht: 30kD

Gen-ID: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis