NEK3 Antikörper

Produktnummer ABIN7229960

Der Kaninchen Polyklonal anti-NEK3 Antikörper wird verwendet zum Nachweis von NEK3 in Proben von Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für NEK3 Antikörper (ABIN7229960)

Target: NEK3 (NIMA related kinase 3 (NEK3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NEK3 Antikörper

Verwendungszweck: Rabbit Anti-NEK3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NEK3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NEK3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NEK3

Target: NEK3 (NIMA related kinase 3 (NEK3))

Andere Bezeichnung: NEK3

Hintergrund: Serine/threonine-protein kinase Nek3, HSPK 36, Never in mitosis A-related kinase 3, NimA-related protein kinase 3NEK3 encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. NIMA Related Kinase 3 differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 55kD

Gen-ID: 4752

UniProt: P51956