NPY1R Antikörper (AA 190-270)

Produktnummer ABIN7222812

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NPY1R in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NPY1R Antikörper (AA 190-270) (ABIN7222812)

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPY1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-NPY1R Antikörper

Bindungsspezifität: AA 190-270

Verwendungszweck: Rabbit Anti-NPY1-R Polyclonal Antibody

Spezifität: NPY1-R Polyclonal Antibody detects endogenous levels of NPY1-R protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NPY1-R at AA range: 190-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NPY1R

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Andere Bezeichnung: NPY1-R

Hintergrund: NPY1R, NPYR, NPYY1, Neuropeptide Y receptor type 1, NPY1-RNPY1R belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.

Molekulargewicht: 48kD

Gen-ID: 4886

UniProt: P25929

Pathways: Negative Regulation of Hormone Secretion, Feeding Behaviour