Neuromedin B Antikörper (AA 20-100)

Produktnummer ABIN7230032

Der Kaninchen Polyklonal anti-Neuromedin B Antikörper wird verwendet zum Nachweis von Neuromedin B in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Neuromedin B Antikörper (AA 20-100) (ABIN7230032)

Target: Neuromedin B

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuromedin B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Neuromedin B Antikörper

Bindungsspezifität: AA 20-100

Verwendungszweck: Rabbit Anti-NMB Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NMB protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NMB protein at AA range: 20-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Neuromedin B

Target: Neuromedin B

Andere Bezeichnung: NMB

Hintergrund: Neuromedin-BNMB (Neuromedin B) is a Protein Coding gene. Diseases associated with NMB include Gastrinoma and Neuronal Ceroid Lipofuscinosis. Among its related pathways are Signaling by GPCR and RET signaling. NMB encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of NMB may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 13kD

Gen-ID: 4828

UniProt: P08949