NET1 Antikörper (AA 230-310)

Produktnummer ABIN7227362

Der Kaninchen Polyklonal anti-NET1 Antikörper (ABIN7227362) detektiert spezifisch NET1 in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für NET1 Antikörper (AA 230-310) (ABIN7227362)

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NET1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-NET1 Antikörper

Bindungsspezifität: AA 230-310

Verwendungszweck: Rabbit Anti-ARHG8 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ARHG8 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ARHG8 protein at AA range: 230-310

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NET1

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Andere Bezeichnung: ARHG8

Hintergrund: Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8NET1 (Neuroepithelial Cell Transforming 1) is a Protein Coding gene. Diseases associated with NET1 include Breast Cancer. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway. NET1 is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by NET1 interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of NET1 are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Molekulargewicht: 65kD

Gen-ID: 10276

UniProt: Q7Z628

Pathways: Neurotrophin Signalübertragung