UNC5B Antikörper (AA 350-430)

Produktnummer ABIN7232040

Der Kaninchen Polyklonal anti-UNC5B Antikörper wird verwendet zum Nachweis von UNC5B in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für UNC5B Antikörper (AA 350-430) (ABIN7232040)

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UNC5B Antikörper

Bindungsspezifität: AA 350-430

Verwendungszweck: Rabbit Anti-UNC5B Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of UNC5B protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human UNC5B protein at AA range: 350-430

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu UNC5B

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Andere Bezeichnung: UNC5B

Hintergrund: Netrin receptor UNC5B, Protein unc-5 homolog 2, Protein unc-5 homolog B, p53-regulated receptor for death and life protein 1, p53RDL1UNC5B (Unc-5 Netrin Receptor B) is a Protein Coding gene. Among its related pathways are Netrin-1 signaling and Netrin Signaling. UNC5B encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for UNC5B.

Molekulargewicht: 103kD

Gen-ID: 219699

UniProt: Q8IZJ1