NCK1 Antikörper
Kurzübersicht für NCK1 Antikörper (ABIN7229918)
Target
Alle NCK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NCK1 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of NCK1 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human NCK1 protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NCK1 (NCK Adaptor Protein 1 (NCK1))
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Andere Bezeichnung
- NCK1
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Hintergrund
- Rabbit Anti-NCK1 Polyclonal Antibody,Cytoplasmic protein NCK1, NCK adaptor protein 1, Nck-1, SH2/SH3 adaptor protein NCK-alpha,NCK1 (NCK Adaptor Protein 1) is a Protein Coding gene. Diseases associated with NCK1 include Wiskott-Aldrich Syndrome and Multiple Endocrine Neoplasia Iib. Among its related pathways are Netrin-1 signaling and Arf6 signaling events. The protein encoded by NCK1 is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.,NCK1
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Molekulargewicht
- observerd band 41kDa
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Gen-ID
- 4690
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UniProt
- P16333
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Pathways
- T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Target
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