Der Kaninchen Polyklonal anti-NBPF1,9,10,12,14,15,16,20 Antikörper (ABIN7215966) detektiert spezifisch NBPF1,9,10,12,14,15,16,20 in ELISA, WB, IHC und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
Alexa Fluor 594
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
NBPF1,9,10,12,14,15,16,20
Andere Bezeichnung
NBPF1/9/10/12/14/15/16/20
Hintergrund
NBPF12, COAS1, KIAA1245, Neuroblastoma breakpoint family member 12, Chromosome 1 amplified sequence 1, NBPF10, Neuroblastoma breakpoint family member 10, NBPF16, Neuroblastoma breakpoint family member 16, NBPF1, KIAA1693, Neuroblastoma breaNBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21. , where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.