MPRIP Antikörper (Internal Region)

Produktnummer ABIN7216892

Dieser Anti-MPRIP Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MPRIP in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MPRIP Antikörper (Internal Region) (ABIN7216892)

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPRIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MPRIP Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: M-RIP Polyclonal Antibody

Spezifität: M-RIP Polyclonal Antibody detects endogenous levels of M-RIP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human M-RIP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Andere Bezeichnung: M-RIP

Hintergrund: Rabbit Anti-M-RIP Polyclonal Antibody,MPRIP, KIAA0864, MRIP, RHOIP3, Myosin phosphatase Rho-interacting protein, M-RIP, Rho-interacting protein 3, RIP3, p116Rip,MPRIP (Myosin Phosphatase Rho Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding. Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.,Myosin phosphatase Rho-interacting protein

Molekulargewicht: observerd band 115kDa

Gen-ID: 23164

UniProt: Q6WCQ1