Der Kaninchen Polyklonal anti-MEGF9 Antikörper (ABIN7214686) detektiert spezifisch MEGF9 in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
MEGF9
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
APC
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
MEGF9
(Multiple EGF-Like-Domains 9 (MEGF9))
Andere Bezeichnung
EGFL5
Hintergrund
MEGF9, EGFL5, KIAA0818, Multiple epidermal growth factor-like domains protein 9, Multiple EGF-like domains protein 9, Epidermal growth factor-like protein 5, EGF-like protein 5MEGF9 (Multiple EGF-like domains protein 9, also EGF-like protein 5) is a 63 kDa (predicted) novel transmembrane glycoprotein that shares some homology to beta -chains of laminin. It is expressed by hepatocytes, cerebellar Purkinje cells, Schwann cells, keratinocytes and intestinal epithelium. MEGF9 is suggested to participate in cell motility, and its absence correlates with tumor cell migration. Mature human MEGF9 is 572 amino acids (aa) in length. It is a single span type I transmembrane protein that contains a 484 aa extracellular region (aa 31-514) plus a 68 aa C-terminal cytoplasmic domain. The extracellular region possesses a lengthy Pro-rich region (aa 55-200), followed by five EGF-like domains (aa 204-451). MEGF9 may run at approximately 160 kDa in SDS-PAGE, suggesting either heavy glycosylation or dimerization. Over aa 36-514, human MEGF9 shares 76 % aa sequence identity with mouse MEGF9.