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MLK1/2 Antikörper (pThr266, pThr312)

Dieser Anti-MLK1/2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MLK1/2 in ELISA und IHC (p). Geeignet für Human und Maus.
Produktnummer ABIN7222484

Kurzübersicht für MLK1/2 Antikörper (pThr266, pThr312) (ABIN7222484)

Target

MLK1/2

Reaktivität

Human, Maus

Wirt

  • 12
Kaninchen

Klonalität

  • 12
Polyklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MLK1/2 Antikörper ist unkonjugiert

Applikation

  • 5
  • 4
  • 2
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 10
    • 8
    • 1
    • 1
    • 1
    pThr266, pThr312

    Verwendungszweck

    MLK1/2 (phospho Thr312/266) Polyclonal Antibody

    Spezifität

    Phospho-MLK1/2 (T312/266) Polyclonal Antibody detects endogenous levels of MLK1/2 protein only when phosphorylated at T312/266.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from human MLK1/2 Phospho-Thr312/266

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    Kommentare

    Primary Antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    MLK1/2

    Hintergrund

    Rabbit Anti-MLK1/2 (phospho Thr312/266) Polyclonal Antibody,MAP3K9, MLK1, PRKE1, Mitogen-activated protein kinase kinase kinase 9, Mixed lineage kinase 1, MAP3K10, MLK2, MST, Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST,The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.,Mitogen-activated protein kinase kinase kinase 9

    Gen-ID

    4293, 4294
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