MAP4K5 Antikörper (AA 300-380)

Produktnummer ABIN7229500

Der Kaninchen Polyklonal anti-MAP4K5 Antikörper wird verwendet zum Nachweis von MAP4K5 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für MAP4K5 Antikörper (AA 300-380) (ABIN7229500)

Target: MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP4K5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MAP4K5 Antikörper

Bindungsspezifität: AA 300-380

Verwendungszweck: Rabbit Anti-M4K5 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of M4K5 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human M4K5 protein at AA range: 300-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MAP4K5

Target: MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))

Andere Bezeichnung: M4K5

Hintergrund: Mitogen-activated protein kinase kinase kinase kinase 5, Kinase homologous to SPS1/STE20, KHS, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, MEKKK 5MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5) encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for MAP4K5. MAP4K5 is a Protein Coding gene. Diseases associated with MAP4K5 include Dysgraphia and Writing Disorder. Among its related pathways are TGF-Beta Pathway and Angiopoietin Like Protein 8 Regulatory Pathway.

Molekulargewicht: 93kD

Gen-ID: 11183

UniProt: Q9Y4K4