MID1 Antikörper (AA 40-120)

Produktnummer ABIN7215760

Der Kaninchen Polyklonal Anti-MID1 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, MID1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für MID1 Antikörper (AA 40-120) (ABIN7215760)

Target: MID1 (Midline 1 (MID1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MID1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MID1 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: Midline-1 Polyclonal Antibody

Spezifität: Midline-1 Polyclonal Antibody detects endogenous levels of Midline-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Midline-1 at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MID1

Target: MID1 (Midline 1 (MID1))

Andere Bezeichnung: Midline-1

Hintergrund: Rabbit Anti-Midline-1 Polyclonal Antibody,MID1, FXY, RNF59, TRIM18, XPRF, Midline-1, Midin, Midline 1 RING finger protein, Putative transcription factor XPRF, RING finger protein 59, Tripartite motif-containing protein 18,Midline-1 encoded by this MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. Midline-1 is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing, however, the full-length nature of some of the variants has not been determined.,Midline-1

Molekulargewicht: observerd band 75kDa

Gen-ID: 4281

UniProt: O15344