Manic Fringe Antikörper (AA 30-110)

Produktnummer ABIN7222460

Der Kaninchen-Polyklonal Anti-Manic Fringe-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von Manic Fringe in Proben aus Human, Maus und Ratte. }

Kurzübersicht für Manic Fringe Antikörper (AA 30-110) (ABIN7222460)

Target: Manic Fringe (MFNG) (MFNG)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Manic Fringe Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Manic Fringe Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: Manic Fringe Polyclonal Antibody

Spezifität: Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Manic Fringe at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Manic Fringe

Target: Manic Fringe (MFNG) (MFNG)

Andere Bezeichnung: Manic Fringe

Hintergrund: Rabbit Anti-Manic Fringe Polyclonal Antibody,MFNG, Beta-1, 3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,MFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.,Beta-1,3-N-acetylglucosaminyltransferase manic fringe

Molekulargewicht: observerd band 38kDa

Gen-ID: 4242

UniProt: O00587

Pathways: Notch Signalweg