METTL3 Antikörper (AA 140-220)

Produktnummer ABIN7217640

Dieser Anti-METTL3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von METTL3 in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für METTL3 Antikörper (AA 140-220) (ABIN7217640)

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METTL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-METTL3 Antikörper

Bindungsspezifität: AA 140-220

Verwendungszweck: M6A Polyclonal Antibody

Spezifität: M6A Polyclonal Antibody detects endogenous levels of M6A protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human M6A at AA range: 140-220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Andere Bezeichnung: M6A

Hintergrund: Rabbit Anti-M6A Polyclonal Antibody,GPM6A, M6A, Neuronal membrane glycoprotein M6-a, M6a,GPM6A (Glycoprotein M6A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium channel activity. An important paralog of this gene is PLP1. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), enhances internalization and recycling of mu-type opioid receptor.,Neuronal membrane glycoprotein M6-a

Molekulargewicht: observerd band 31kDa

Gen-ID: 2823

UniProt: P51674