MerTK/Tyro3 Antikörper (pTyr681, pTyr749)

Produktnummer ABIN7218994

Der Kaninchen Polyklonal anti-MerTK/Tyro3 Antikörper wird verwendet zum Nachweis von MerTK/Tyro3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für MerTK/Tyro3 Antikörper (pTyr681, pTyr749) (ABIN7218994)

Target: MerTK/Tyro3

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MerTK/Tyro3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MerTK/Tyro3 Antikörper

Bindungsspezifität: pTyr681, pTyr749

Verwendungszweck: Rabbit Anti-MerTK/Tyro3 (phospho Tyr749/681) Polyclonal Antibody

Spezifität: Phospho-MerTK/Tyro3 (Y749/681) Polyclonal Antibody detects endogenous levels of MerTK/Tyro3 protein only when phosphorylated at Y749/681.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human MerTK/Tyro3 Phospho-Tyr749/681

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MerTK/Tyro3

Target: MerTK/Tyro3

Andere Bezeichnung: MerTK/Tyro3

Hintergrund: MERTK, MER, Tyrosine-protein kinase Mer, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, TYRO3, BYK, DTK, RSE, SKY, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinMERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Molekulargewicht: 97kD

Gen-ID: 10461, 7301

UniProt: Q12866, Q06418