MAGED2 Antikörper (AA 120-200)

Produktnummer ABIN7229540

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAGED2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MAGED2 Antikörper (AA 120-200) (ABIN7229540)

Target: MAGED2 (Melanoma Antigen Family D, 2 (MAGED2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGED2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MAGED2 Antikörper

Bindungsspezifität: AA 120-200

Verwendungszweck: Rabbit Anti-MAGD2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MAGD2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGD2 protein at AA range: 120-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MAGED2

Target: MAGED2 (Melanoma Antigen Family D, 2 (MAGED2))

Andere Bezeichnung: MAGD2

Hintergrund: Melanoma-associated antigen D2, 11B6, Breast cancer-associated gene 1 protein, BCG-1, Hepatocellular carcinoma-associated protein JCL-1, MAGE-D2 antigenMAGED2 (MAGE Family Member D2) is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. MAGED2 is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in MAGED2 cause a form of transient antenatal Bartter's syndrome. MAGED2 may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by MAGED2 is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 66kD

Gen-ID: 10916

UniProt: Q9UNF1