MAGEB1 Antikörper (AA 70-150)

Produktnummer ABIN7229524

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAGEB1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MAGEB1 Antikörper (AA 70-150) (ABIN7229524)

Target: MAGEB1 (Melanoma Antigen Family B, 1 (MAGEB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MAGEB1 Antikörper

Bindungsspezifität: AA 70-150

Verwendungszweck: Rabbit Anti-MAGB1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MAGB1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGB1 protein at AA range: 70-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MAGEB1

Target: MAGEB1 (Melanoma Antigen Family B, 1 (MAGEB1))

Andere Bezeichnung: MAGB1

Hintergrund: Melanoma-associated antigen B1, Cancer/testis antigen 3.1, CT3.1, DSS-AHC critical interval MAGE superfamily 10, DAM10, MAGE-B1 antigen, MAGE-XP antigenMAGEB1 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 % sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB1 is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. MAGEB1 and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for MAGEB1, however, the full length nature of some variants has not been defined. MAGEB4 is expressed in testis.

Molekulargewicht: 38kD

Gen-ID: 4112

UniProt: P43366