MATK Antikörper (Internal Region)

Produktnummer ABIN7222372

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MATK in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MATK Antikörper (Internal Region) (ABIN7222372)

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MATK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MATK Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-Lsk Polyclonal Antibody

Spezifität: Lsk Polyclonal Antibody detects endogenous levels of Lsk protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Lsk

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Andere Bezeichnung: Lsk

Hintergrund: MATK, CTK, HYL, Megakaryocyte-associated tyrosine-protein kinase, CSK homologous kinase, CHK, Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTKThe protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: sRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Molekulargewicht: 56kD

Gen-ID: 4145

UniProt: P42679