MMP15 Antikörper (AA 580-660)

Produktnummer ABIN7222514

Der Kaninchen Polyklonal anti-MMP15 Antikörper wird verwendet zum Nachweis von MMP15 in Proben von Human und Maus. Er wurde validiert für WB und IHC.

Kurzübersicht für MMP15 Antikörper (AA 580-660) (ABIN7222514)

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MMP15 Antikörper

Bindungsspezifität: AA 580-660

Verwendungszweck: Rabbit Anti-MMP-15 Polyclonal Antibody

Spezifität: MMP-15 Polyclonal Antibody detects endogenous levels of MMP-15 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human MMP-15 at AA range: 580-660

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MMP15

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Andere Bezeichnung: MMP-15

Hintergrund: MMP15, Matrix metalloproteinase-15, MMP-15, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2MMP15 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression.

Molekulargewicht: 80kD

Gen-ID: 4324

UniProt: P51511