LRP1B Antikörper (AA 200-280)

Produktnummer ABIN7229444

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch LRP1B in IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für LRP1B Antikörper (AA 200-280) (ABIN7229444)

Target: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP1B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LRP1B Antikörper

Bindungsspezifität: AA 200-280

Verwendungszweck: LRP1B Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of LRP1B protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human LRP1B protein at AA range: 200-280

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu LRP1B

Target: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Andere Bezeichnung: LRP1B

Hintergrund: Rabbit Anti-LRP1B Polyclonal Antibody,Low-density lipoprotein receptor-related protein 1B, LRP-1B, Low-density lipoprotein receptor-related protein-deleted in tumor, LRP-DIT,LRP1B is a putative tumor suppressor and a member of the low-density lipoprotein (LDL) receptor family. The LDL receptor family have roles related to clearance of extracellular ligand and are proposed to be involved in extracellular signal transduction. silencing and down-expression of LRP1B as been observed in renal cell carcinoma and thyroid cancer. Further Deletion of LRP1B has been associated with chemotherapy resistance in high-grade serous cancers.,LRP1B

Molekulargewicht: observerd band 505kDa

Gen-ID: 53353

UniProt: Q9NZR2