LMTK3 Antikörper (AA 1220-1300)

Produktnummer ABIN7219336

Der Kaninchen Polyklonal anti-LMTK3 Antikörper wird verwendet zum Nachweis von LMTK3 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für LMTK3 Antikörper (AA 1220-1300) (ABIN7219336)

Target: LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMTK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-LMTK3 Antikörper

Bindungsspezifität: AA 1220-1300

Verwendungszweck: Rabbit Anti-LMTK3 Polyclonal Antibody

Spezifität: LMTK3 Polyclonal Antibody detects endogenous levels of LMTK3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human LMTK3 at AA range: 1220-1300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu LMTK3

Target: LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))

Andere Bezeichnung: LMTK3

Hintergrund: LMTK3, KIAA1883, TYKLM3, Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).

Molekulargewicht: 153kD

Gen-ID: 114783

UniProt: Q96Q04