LMTK3 Antikörper (AA 1220-1300)

Produktnummer ABIN7219336

Der Kaninchen-Polyklonal Anti-LMTK3-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet zum Nachweis von LMTK3 in Proben aus Human und Maus. }

Kurzübersicht für LMTK3 Antikörper (AA 1220-1300) (ABIN7219336)

Target: LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMTK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LMTK3 Antikörper

Bindungsspezifität: AA 1220-1300

Verwendungszweck: LMTK3 Polyclonal Antibody

Spezifität: LMTK3 Polyclonal Antibody detects endogenous levels of LMTK3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human LMTK3 at AA range: 1220-1300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu LMTK3

Target: LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))

Andere Bezeichnung: LMTK3

Hintergrund: Rabbit Anti-LMTK3 Polyclonal Antibody,LMTK3, KIAA1883, TYKLM3, Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3,LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).,serine threonine-protein kinase LMTK3

Molekulargewicht: observerd band 40kDa

Gen-ID: 114783

UniProt: Q96Q04