Latrophilin 1 Antikörper (AA 530-610)

Produktnummer ABIN7220562

Der Kaninchen Polyklonal Anti-Latrophilin 1 Antikörper wurde für ELISA und IF validiert. Er ist geeignet, Latrophilin 1 in Proben von Ratte, Human und Maus zu detektieren.

Kurzübersicht für Latrophilin 1 Antikörper (AA 530-610) (ABIN7220562)

Target: Latrophilin 1 (LPHN1)

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Latrophilin 1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-Latrophilin 1 Antikörper

Bindungsspezifität: AA 530-610

Verwendungszweck: Latrophilin-1 Polyclonal Antibody

Spezifität: Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Latrophilin-1 at AA range: 530-610

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Latrophilin 1

Target: Latrophilin 1 (LPHN1)

Andere Bezeichnung: Latrophilin-1

Hintergrund: Rabbit Anti-Latrophilin-1 Polyclonal Antibody,LPHN1, KIAA0821, LEC2, Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2,ADGRL1 encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.,Latrophilin-1

Gen-ID: 22859

UniProt: O94910

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis