LARP1 Antikörper

Produktnummer ABIN7229354

Der Kaninchen Polyklonal anti-LARP1 Antikörper wird verwendet zum Nachweis von LARP1 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für LARP1 Antikörper (ABIN7229354)

Target: LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LARP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LARP1 Antikörper

Verwendungszweck: Rabbit Anti-LARP1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of LARP1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LARP1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu LARP1

Target: LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))

Andere Bezeichnung: LARP1

Hintergrund: La-related protein 1, La ribonucleoprotein domain family member 1LARP1 (La Ribonucleoprotein Domain Family Member 1) is a Protein Coding gene. Among its related pathways are Translational Control. RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex Associates with the mRNA 5cap in an MTOR-dependent manner and associates with mRNAs containing a 5 terminal oligopyrimidine (5TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5TOP, thereby regulating cell growth and proliferation Positively regulates the replication of dengue virus

Molekulargewicht: 120kD

Gen-ID: 23367

UniProt: Q6PKG0

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion