Kininogen-1 Heavy Chain (AA 300-380), (Cleaved-Lys380) Antikörper

Produktnummer ABIN7222046

Dieser Anti-not_set Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von not_set in ELISA und WB. Geeignet für Human.

Kurzübersicht für Kininogen-1 Heavy Chain (AA 300-380), (Cleaved-Lys380) Antikörper (ABIN7222046)

Target: Kininogen-1 Heavy Chain

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 300-380, Cleaved-Lys380

Verwendungszweck: Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody

Spezifität: Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody detects endogenous levels of fragment of activated Kininogen-1 HC protein resulting from cleavage adjacent to K380.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Kininogen-1 HC at AA range: 300-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: Kininogen-1 Heavy Chain

Andere Bezeichnung: Kininogen-1 HC

Hintergrund: Rabbit Anti-Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody,KNG1, BDK, KNG, Kininogen-1, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Williams-Fitzgerald-Flaujeac factor,KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.,Kininogen-1

Molekulargewicht: observerd band 41kDa

Gen-ID: 3827

UniProt: P01042