KSR2 Antikörper (AA 640-720)

Produktnummer ABIN7221194

Der Kaninchen Polyklonal anti-KSR2 Antikörper (ABIN7221194) detektiert spezifisch KSR2 in ELISA, WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für KSR2 Antikörper (AA 640-720) (ABIN7221194)

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KSR2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-KSR2 Antikörper

Bindungsspezifität: AA 640-720

Verwendungszweck: Rabbit Anti-Ksr2 Polyclonal Antibody

Spezifität: Ksr2 Polyclonal Antibody detects endogenous levels of Ksr2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Ksr2 at AA range: 640-720

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KSR2

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Andere Bezeichnung: Ksr2

Hintergrund: KSR2, Kinase suppressor of Ras 2, hKSR2Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Molekulargewicht: 108kD

Gen-ID: 283455

UniProt: Q6VAB6