KRT8 Antikörper

Produktnummer ABIN7229280

Der Kaninchen Polyklonal Anti-KRT8 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, KRT8 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für KRT8 Antikörper (ABIN7229280)

Target: KRT8 (Keratin 8 (KRT8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KRT8 Antikörper

Verwendungszweck: Keratin 8 Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of Keratin 8.

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Keratin 8 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu KRT8

Target: KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung: Keratin 8

Hintergrund: Rabbit Anti-Keratin 8 Polyclonal Antibody,Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8,KRT8 (Keratin 8) is a Protein Coding gene. Diseases associated with KRT8 include Cirrhosis, Cryptogenic and Hidrocystoma. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization. KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.,Keratin 8

Molekulargewicht: observerd band 53kDa

Gen-ID: 3856

UniProt: P05787