KRT4 Antikörper (AA 200-260)

Produktnummer ABIN7228142

Der Kaninchen Polyklonal anti-KRT4 Antikörper wird verwendet zum Nachweis von KRT4 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für KRT4 Antikörper (AA 200-260) (ABIN7228142)

Target: KRT4 (Keratin 4 (KRT4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KRT4 Antikörper

Bindungsspezifität: AA 200-260

Verwendungszweck: Rabbit Anti-Cytokeratin 4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of Cytokeratin 4

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Cytokeratin 4 protein at AA range: 200-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KRT4

Target: KRT4 (Keratin 4 (KRT4))

Andere Bezeichnung: Cytokeratin 4

Hintergrund: Keratin, type II cytoskeletal 4, Cytokeratin-4, CK-4, Keratin-4, K4, Type-II keratin Kb4The protein encoded by KRT4 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. KRT4 (Keratin 4) is a Protein Coding gene. Diseases associated with KRT4 include White Sponge Nevus 1 and White Sponge Nevus Of Cannon, Krt4-Related. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization.

Molekulargewicht: 57kD

UniProt: P19013