Cytokeratin 13 Antikörper (Internal Region)
Kurzübersicht für Cytokeratin 13 Antikörper (Internal Region) (ABIN7214478)
Target
Alle Cytokeratin 13 (KRT13) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Verwendungszweck
- Rabbit Anti-Cytokeratin 13 Polyclonal Antibody
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Spezifität
- Cytokeratin 13 Polyclonal Antibody detects endogenous levels of Cytokeratin 13 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from the Internal region of human Cytokeratin 13
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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Andere Bezeichnung
- Cytokeratin 13
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Hintergrund
- KRT13, Keratin, type I cytoskeletal 13, Cytokeratin-13, CK-13, Keratin-13, K13Keratin 13 encoded by KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of KRT13 results in multiple transcript variants, however, not all variants have been described.
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Molekulargewicht
- 52kD
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Gen-ID
- 3860
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UniProt
- P13646
Target
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