JTB Antikörper (AA 20-100)

Produktnummer ABIN7219176

Der Kaninchen Polyklonal anti-JTB Antikörper wird verwendet zum Nachweis von JTB in Proben von Human, Ratte und Maus. Er wurde validiert für WB und IHC.

Kurzübersicht für JTB Antikörper (AA 20-100) (ABIN7219176)

Target: JTB (Jumping Translocation Breakpoint (JTB))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-JTB Antikörper

Bindungsspezifität: AA 20-100

Verwendungszweck: Rabbit Anti-JTB Polyclonal Antibody

Spezifität: JTB Polyclonal Antibody detects endogenous levels of JTB protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human JTB at AA range: 20-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu JTB

Target: JTB (Jumping Translocation Breakpoint (JTB))

Andere Bezeichnung: JTB

Hintergrund: JTB, HSPC222, Protein JTB, Jumping translocation breakpoint protein, Prostate androgen-regulated protein, PAR proteinRequired for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

Molekulargewicht: 17kD

Gen-ID: 10899

UniProt: O76095