JTB Antikörper (AA 20-100)

Produktnummer ABIN7219176

Der Kaninchen Polyklonal Anti-JTB Antikörper wurde für WB und ELISA validiert. Er ist geeignet, JTB in Proben von Human zu detektieren.

Kurzübersicht für JTB Antikörper (AA 20-100) (ABIN7219176)

Target: JTB (Jumping Translocation Breakpoint (JTB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-JTB Antikörper

Bindungsspezifität: AA 20-100

Verwendungszweck: JTB Polyclonal Antibody

Spezifität: JTB Polyclonal Antibody detects endogenous levels of JTB protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human JTB at AA range: 20-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu JTB

Target: JTB (Jumping Translocation Breakpoint (JTB))

Andere Bezeichnung: JTB

Hintergrund: Rabbit Anti-JTB Polyclonal Antibody,JTB, HSPC222, Protein JTB, Jumping translocation breakpoint protein, Prostate androgen-regulated protein, PAR protein,Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.,Protein JTB

Molekulargewicht: observerd band 17kDa

Gen-ID: 10899

UniProt: O76095