ITIH4 Antikörper (Cleaved-Arg661)
Kurzübersicht für ITIH4 Antikörper (Cleaved-Arg661) (ABIN7221914)
Target
Alle ITIH4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 590-670, Cleaved-Arg661
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Verwendungszweck
- Rabbit Anti-Cleaved-ITI-H4 70k (R661) Polyclonal Antibody
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Spezifität
- Cleaved-ITI-H4 70k (R661) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H4 70k protein resulting from cleavage adjacent to R661.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from the Internal region of human ITI-H4 70k at AA range: 590-670
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))
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Andere Bezeichnung
- ITI-H4 70k
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Hintergrund
- ITIH4, IHRP, ITIHL1, PK120, Inter-alpha-trypsin inhibitor heavy chain H4, ITI heavy chain H4, ITI-HC4, Inter-alpha-inhibitor heavy chain 4, Inter-alpha-trypsin inhibitor family heavy chain-related protein, IHRP, Plasma kallikrein sensitiveThe protein encoded by ITIH4 is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene.
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Gen-ID
- 3700
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UniProt
- Q14624
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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