IFNGR1 Antikörper (pTyr457)

Produktnummer ABIN7221690

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IFNGR1 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für IFNGR1 Antikörper (pTyr457) (ABIN7221690)

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNGR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IFNGR1 Antikörper

Bindungsspezifität: pTyr457

Verwendungszweck: IFN-γRα (phospho Tyr457) Polyclonal Antibody

Spezifität: Phospho-IFN-γRα (Y457) Polyclonal Antibody detects endogenous levels of IFN-γRα protein only when phosphorylated at Y457.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human IFN-gammaRalpha Phospho-Tyr457

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Andere Bezeichnung: IFN-gammaRalpha

Hintergrund: Rabbit Anti-IFN-γRα (phospho Tyr457) Polyclonal Antibody,IFNGR1, Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, CD antigen CD119,IFNGR1encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.,Interferon gamma receptor 1

Molekulargewicht: observerd band 83kDa

Gen-ID: 3459

UniProt: P15260

Pathways: Interferon-gamma Pathway