ITLN1/Omentin Antikörper (AA 110-190)

Produktnummer ABIN7229202

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ITLN1/Omentin in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ITLN1/Omentin Antikörper (AA 110-190) (ABIN7229202)

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITLN1/Omentin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ITLN1/Omentin Antikörper

Bindungsspezifität: AA 110-190

Verwendungszweck: ITLN1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ITLN1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ITLN1 protein at AA range: 110-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ITLN1/Omentin

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Andere Bezeichnung: ITLN1

Hintergrund: Rabbit Anti-ITLN1 Polyclonal Antibody,Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin,ITLN1 (Intelectin 1) is a Protein Coding gene. Diseases associated with ITLN1 include Obesity and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is ITLN2. Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed: 11313366, PubMed: 26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed: 26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K. neumoniae, S. neumoniae, Y. estis, P. irabilis and P. ulgaris (PubMed: 26148048). Does not bind human glycans (PubMed: 26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed: 16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed: 16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed: 11747454, PubMed: 23921499).,ITLN1

Molekulargewicht: observerd band 34kDa

Gen-ID: 55600

UniProt: Q8WWA0