ITGB3BP Antikörper (AA 10-90)

Produktnummer ABIN7227848

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch ITGB3BP in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ITGB3BP Antikörper (AA 10-90) (ABIN7227848)

Target: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGB3BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ITGB3BP Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: CENPR Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CENPR protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CENPR protein at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ITGB3BP

Target: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Andere Bezeichnung: CENPR

Hintergrund: Rabbit Anti-CENPR Polyclonal Antibody,Centromere protein R, CENP-R, Beta-3-endonexin, Integrin beta-3-binding protein, Nuclear receptor-interacting factor 3,ITGB3BP (Integrin Subunit Beta 3 Binding Protein) encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. ITGB3BP also acts as a corepressor of NF-kappaB-dependent signaling. ITGB3BP induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. ITGB3BP is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.,CENPR

Molekulargewicht: observerd band 19kDa

Gen-ID: 23421

UniProt: Q13352

Pathways: Neurotrophin Signalübertragung