ITGB1BP2 Antikörper (AA 10-90)

Produktnummer ABIN7229198

Der Kaninchen Polyklonal anti-ITGB1BP2 Antikörper wird verwendet zum Nachweis von ITGB1BP2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für ITGB1BP2 Antikörper (AA 10-90) (ABIN7229198)

Target: ITGB1BP2 (Integrin beta 1 Binding Protein (Melusin) 2 (ITGB1BP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGB1BP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ITGB1BP2 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Rabbit Anti-ITBP2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ITBP2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ITBP2 protein at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ITGB1BP2

Target: ITGB1BP2 (Integrin beta 1 Binding Protein (Melusin) 2 (ITGB1BP2))

Andere Bezeichnung: ITBP2

Hintergrund: Integrin beta-1-binding protein 2, MelusinITGB1BP2 encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of ITGB1BP2 indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains.

Molekulargewicht: 38kD

Gen-ID: 26548

UniProt: Q9UKP3