Integrin AlphaV HC (AA 810-890), (Cleaved-Lys889) Antikörper

Produktnummer ABIN7212526

Der Kaninchen Polyklonal anti-Integrin AlphaV HC Antikörper (ABIN7212526) detektiert spezifisch Integrin AlphaV HC in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Integrin AlphaV HC (AA 810-890), (Cleaved-Lys889) Antikörper (ABIN7212526)

Target: Integrin AlphaV HC

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 810-890, Cleaved-Lys889

Verwendungszweck: Cleaved-Integrin αV HC (K889) Polyclonal Antibody

Spezifität: Cleaved-Integrin αV HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin αV HC protein resulting from cleavage adjacent to K889.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Integrin alphaV HC at AA range: 810-890

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: Integrin AlphaV HC

Hintergrund: Rabbit Anti-Cleaved-Integrin αV HC (K889) Polyclonal Antibody,ITGAV, MSK8, VNRA, Integrin alpha-V, Vitronectin receptor subunit alpha, CD antigen CD51,The product of ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.,Integrin alpha-V

Molekulargewicht: observerd band 95kDa

Gen-ID: 3685

UniProt: P06756