ITGA7 Antikörper (Cleaved-Glu959)

Produktnummer ABIN7212524

Der Kaninchen Polyklonal anti-ITGA7 Antikörper wird verwendet zum Nachweis von ITGA7 in Proben von Human und Affe. Er wurde validiert für WB und ELISA.

Kurzübersicht für ITGA7 Antikörper (Cleaved-Glu959) (ABIN7212524)

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ITGA7 Antikörper

Bindungsspezifität: AA 910-990, Cleaved-Glu959

Verwendungszweck: Rabbit Anti-Cleaved-Integrin α7 LC (E959) Polyclonal Antibody

Spezifität: Cleaved-Integrin α7 LC (E959) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α7 LC protein resulting from cleavage adjacent to E959.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Integrin alpha7 LC at AA range: 910-990

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ITGA7

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Andere Bezeichnung: Integrin alpha7 LC

Hintergrund: ITGA7, Integrin alpha-7The protein encoded by ITGA7 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis.Integrin subunit alpha 7 functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in ITGA7 are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for ITGA7.

Molekulargewicht: 25kD

Gen-ID: 3679

UniProt: Q13683

Pathways: Integrin Complex