Integrin Alpha6 LC (AA 900-980), (Cleaved-Glu942) Antikörper

Produktnummer ABIN7212522

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Integrin Alpha6 LC in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Integrin Alpha6 LC (AA 900-980), (Cleaved-Glu942) Antikörper (ABIN7212522)

Target: Integrin Alpha6 LC

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 900-980, Cleaved-Glu942

Verwendungszweck: Cleaved-Integrin α6 LC (E942) Polyclonal Antibody

Spezifität: Cleaved-Integrin α6 LC (E942) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α6 LC protein resulting from cleavage adjacent to E942.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Integrin alpha6 LC at AA range: 900-980

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: Integrin Alpha6 LC

Hintergrund: Rabbit Anti-Cleaved-Integrin α6 LC (E942) Polyclonal Antibody,ITGA6, Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD antigen CD49f,ITGA6 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.,Integrin alpha-6

Molekulargewicht: observerd band 28kDa

Gen-ID: 3655

UniProt: P23229