ITFG2 Antikörper (AA 40-120)

Produktnummer ABIN7229200

Der Kaninchen Polyklonal anti-ITFG2 Antikörper wird verwendet zum Nachweis von ITFG2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für ITFG2 Antikörper (AA 40-120) (ABIN7229200)

Target: ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITFG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ITFG2 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: Rabbit Anti-ITFG2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ITFG2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ITFG2 protein at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ITFG2

Target: ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

Andere Bezeichnung: ITFG2

Hintergrund: KICSTOR complex protein ITFG2, Integrin-alpha FG-GAP repeat-containing protein 2ITFG2 (Integrin Alpha FG-GAP Repeat Containing 2) is a Protein Coding gene. Diseases associated with ITFG2 include Distal Arthrogryposis. As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.

Molekulargewicht: 49kD

Gen-ID: 55846

UniProt: Q969R8