INSL3 Antikörper (AA 10-50)

Produktnummer ABIN7229150

Der Kaninchen Polyklonal anti-INSL3 Antikörper wird verwendet zum Nachweis von INSL3 in Proben von Human, Ratte und Maus. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für INSL3 Antikörper (AA 10-50) (ABIN7229150)

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSL3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-INSL3 Antikörper

Bindungsspezifität: AA 10-50

Verwendungszweck: Rabbit Anti-INSL3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of INSL3

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human INSL3 protein at AA range: 10-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu INSL3

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Andere Bezeichnung: INSL3

Hintergrund: Insulin-like 3, Leydig insulin-like peptide, Ley-I-L, Relaxin-like factorINSL3 encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that INSL3 may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in INSL3 may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. INSL3 (Insulin Like 3) is a Protein Coding gene. Diseases associated with INSL3 include Cryptorchidism and Testicular Cancer. Among its related pathways are G alpha(s) signalling events and Signaling by GPCR.

Gen-ID: 3640

UniProt: P51460

Pathways: Hormone Activity, cAMP Metabolic Process