ING3 Antikörper

Produktnummer ABIN7229142

Dieser Anti-ING3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ING3 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ING3 Antikörper (ABIN7229142)

Target: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ING3 Antikörper

Verwendungszweck: ING3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ING3 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ING3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ING3

Target: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Andere Bezeichnung: ING3

Hintergrund: Rabbit Anti-ING3 Polyclonal Antibody,Inhibitor of growth protein 3, p47ING3,Inhibitor Of Growth Family Member 3 encoded by ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.,ING3

Molekulargewicht: observerd band 45kDa

Gen-ID: 54556

UniProt: Q9NXR8