Importin 9 Antikörper

Produktnummer ABIN7229180

Der Kaninchen Polyklonal anti-Importin 9 Antikörper wird verwendet zum Nachweis von Importin 9 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Importin 9 Antikörper (ABIN7229180)

Target: Importin 9 (IPO9)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Importin 9 Antikörper

Verwendungszweck: Rabbit Anti-IPO9 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of IPO9 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IPO9 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Importin 9

Target: Importin 9 (IPO9)

Andere Bezeichnung: IPO9

Hintergrund: Importin-9, Imp9, Ran-binding protein 9, RanBP9IPO9 (Importin 9) is a Protein Coding gene. Diseases associated with IPO9 include Atypical Lipomatous Tumor. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.

Molekulargewicht: 114kD

Gen-ID: 55705

UniProt: Q96P70

Pathways: Protein targeting to Nucleus