Importin 9 Antikörper
Kurzübersicht für Importin 9 Antikörper (ABIN7229180)
Target
Alle Importin 9 (IPO9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- IPO9 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of IPO9 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human IPO9 protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Importin 9 (IPO9)
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Andere Bezeichnung
- IPO9
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Hintergrund
- Rabbit Anti-IPO9 Polyclonal Antibody,Importin-9, Imp9, Ran-binding protein 9, RanBP9,IPO9 (Importin 9) is a Protein Coding gene. Diseases associated with IPO9 include Atypical Lipomatous Tumor. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.,IPO9
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Molekulargewicht
- observerd band 114kDa
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Gen-ID
- 55705
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UniProt
- Q96P70
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Pathways
- Protein targeting to Nucleus
Target
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