IGLL1 Antikörper (N-Term)

Produktnummer ABIN7214048

Der Kaninchen Polyklonal anti-IGLL1 Antikörper (ABIN7214048) detektiert spezifisch IGLL1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für IGLL1 Antikörper (N-Term) (ABIN7214048)

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IGLL1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Rabbit Anti-CD179b Polyclonal Antibody

Spezifität: CD179b Polyclonal Antibody detects endogenous levels of CD179b protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human CD179b

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IGLL1

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Andere Bezeichnung: CD179b

Hintergrund: IGLL1, IGL1, Immunoglobulin lambda-like polypeptide 1, CD179 antigen-like family member B, Ig lambda-5, Immunoglobulin omega polypeptide, Immunoglobulin-related protein 14.1, CD antigen CD179b, IGLC1, Ig lambda-1 chain C regions, IGLC2, IgThe preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. IGLL1 does not undergo rearrangement. Mutations in IGLL1 can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for IGLL1.

Molekulargewicht: 23kD

Gen-ID: 3543

UniProt: P15814, P0CG04, P0CG05, P0CG06, P0CF74, A0M8Q6

Pathways: Regulation of Cell Size