IkappaB-epsilon Antikörper

Produktnummer ABIN7222758

Der Kaninchen Polyklonal Anti-IkappaB-epsilon Antikörper wurde für IF, ELISA, WB und IHC (p) validiert. Er ist geeignet, IkappaB-epsilon in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für IkappaB-epsilon Antikörper (ABIN7222758)

Target: IkappaB-epsilon

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IkappaB-epsilon Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IkappaB-epsilon Antikörper

Verwendungszweck: IκB-ε Polyclonal Antibody

Spezifität: IκB-ε Polyclonal Antibody detects endogenous levels of IκB-ε protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human IkappaB-epsilon around the non-phosphorylation site of S22

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu IkappaB-epsilon

Target: IkappaB-epsilon

Hintergrund: Rabbit Anti-IκB-ε Polyclonal Antibody,NFKBIE, IKBE, NF-kappa-B inhibitor epsilon, NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon,The protein encoded by NFKBIE binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.,NF-kappa-B inhibitor epsilon

Molekulargewicht: observerd band 45kDa

Gen-ID: 4794

UniProt: O00221